In contemporary medicine, numerous medical rubber products play an important role. These products must possess safety and performance characteristics appropriate for their intended use, necessitating adherence to rigorous standards.This article aims to provide a concise summary of the latest standards governing medical rubber products, specifically focusing on rubber closures. We will explore the crucial aspects of biological safety, chemical safety, performance requirements, and physical properties associated with rubber closures, shedding light on the essential considerations required for the development and implementation of safe and effective medical devices.