English Abstract

The Issues of Medical Package Materials and the Feature of Medical Compounding ZELAS™

Ayako KIYATAKE *1
Yumiko SAEKI *2
Yuuko MIYAZAKI *3
*1:R&D Division, Specialty Materials Business Group, Mitsubishi Chemical Corporation. Yokkaichi, Mie, Japan
*2:Mitsubishi Chemical Corporation Specialty Materials Business Group Japan Headquarters, Chuo-ku, Osaka, Japan
*3:Mitsubishi Chemical Corporation Basic Materials Business Group Strategic Planning Headquarters, Aoba-ku, Yokohama, Kanagawa, Japan
Nippon Gomu Kyokaishi,(2023),96(8),210-215 General Review in Japanese

The medical package has renewed to save medicine performances. But existing medical materials have issues, for example, normal PVC includes di (2-ethylhexyl) phthalate (DEHP) and DEHP leaches into the medicine), and PVC adsorbs some chemicals). Our Zelas™ MP series showed low chemical adsorption, which has the potential to replace PVC. Not only PVC replacement, Zelas™ TPS has potential to replace Butyl rubber for closure. Moreover, Mitsubishi Chemical corp. launched Zelas™ CP, which showed low protein adsorption and has potential to replace glass for vials.

Keywords: Medical Device, Package, Tube, Closure, Vial, TPS, Biocompatibility and Anti-protein Adsorption